The following are selected publications and please refer to my CV
) for a complete list.
Development of Machine Learning Tools for Analysis of Genomics Data
- L Xing, S Joun, M Lesperance, K Mackey, X Zhang (2020) Handling highly correlated genes of Single-Cell RNA sequencing data in prediction models Submitted
- Y Xu, L Xing, J Su, X Zhang, W Qiu (2019) Bayesian hierarchical models for SNP discovery from genome-wide association studies, a pseudo-supervised machine learning approach. Scientific Reports. volume 9, Article number: 13686 (2019),
- L Xing, M Lesperance, X Zhang (2019) , Simultaneously prediction of multiple outcomes using revised stacking algorithms. Bioinformatics. Jul 2; btz531.
Development of Biostatistics Tools for Epidemiology
Work on Opitmal Designs of Observational Studies and Clinical Trials
Application to Big Data in Economics
Application in Medical Research
- BC McDonald, LA Flashman, DB Arciniegas DB, RJ Ferguson, L Xing, J Harezlak, GC Sprehn, FM Hammond, AC Maerlender, CL Kruck, KL Gillock, K Frey, RN Wall, AJ Saykin, TW McAllister (2016) Methylphenidate and Memory and Attention Adaptation Training for Persistent Cognitive Symptoms after Traumatic Brain Injury: A Randomized, Placebo-Controlled Trial. Neuropsychopharmacology. Aug;42(9):1766-1775.
- ED Michos, KA Carson, ALC Schneider, PL Lutsey, L Xing, AR Sharrett, A Alonso, L Coker, M Gross, W Post, T Mosley, RF Gottesman (2014) Vitamin D and subclinical cerebrovascular disease: the Atherosclerosis Risk in Communities brain magnetic resonance imaging study. JAMA Neurology. Jul 1; 71(7): 863-871.
- R Yuan, T Nagao, PD Pare, JC Hogg, DD Sin, MW Elliott, L Loy, L Xing, SE Kalloger, JC English, JR Mayo, HO Coxson (2010) Quantification of lung surface area using computed tomography. Respiratory Research. Oct 31; 11:153.
- JV Gosselink, S Hayashi, WM Elliott, L Xing, B Chan, L Yang, C Wright, DD Sin, PD Pare, JA Pierce, RA Pierce, A Patterson, J Cooper, JC Hogg (2010) Differential expression of tissue repair genes in the pathogenesis of chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. Jun 15; 181(12): 1329-35.
- E Tamagawa, K Suda, Y Wei, L Xing, T Mui, Y Li, SF van Eeden, SF Man, DD Sin (2009) Endotoxin-induced translocation of interleukin-6 from lungs to the systemic circulation. Innate Immunity. 2009 Aug; 15(4): 251-8.
- J Yee, MD Sadar, DD Sin, M Kuzyk, L Xing, J Kondra, A McWilliams, SF Man, S Lam (2009) Connective tissue-activating peptide III: a novel blood biomarker for early lung cancer detection. Journal of Clinical Oncology. Jun 10; 27(17): 2787-92.
- WC Tan, C Lo, A Jong, L Xing, MJ Fitzgerald, WM Vollmer, SA Buist, DD Sin; Vancouver Burden of Obstructive Lung Disease (BOLD) Research Group (2009) Marijuana and chronic obstructive lung disease: a population-based study. Canadian Medical Association Journal. Apr 14; 180(8): 814-20.
- SFP Man, L Xing, JE Connett, NR Anthonisen, RA Wise, DP Tashkin, X Zhang, R Vessey, TG Walker, BR Celli and DD Sin (2008) Circulating fibronectin to C-reactive protein ratio and mortality: a biomarker in COPD? European Respiratory Journal. 32:1451-1457.
- E Tamagawa, N Bai, K Morimoto, C Gray, T Mui, K Yatera, X Zhang, L Xing, Y Li, I Laher, DD Sin, SFP Man, SF van Eeden (2008) Particulate matter exposure induces persistent lung inflammation and endothelial dysfunction. American Journal of Physiology - Lung Cellular and Molecular Physiology. 295: L79-L85.
- H Coxson, B Quiney, DD Sin, L Xing, AM McWilliams, JR Mayo, S Lam (2008) Airway Thickness Assessed Using Computed Tomography and Optical Coherence Tomography. American Journal of Respiratory and Critical Care Medicine. Jun 1; 177(11): 1201-6.